{"id":3967,"date":"2024-02-26T10:20:50","date_gmt":"2024-02-26T10:20:50","guid":{"rendered":"https:\/\/staging.aliathbio.com\/?p=3967"},"modified":"2024-02-26T13:12:14","modified_gmt":"2024-02-26T13:12:14","slug":"peptomyc-precision-medicine","status":"publish","type":"post","link":"https:\/\/staging.aliathbio.com\/?p=3967","title":{"rendered":"MYC targeting by OMO-103 in solid tumors: a phase 1 trial"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3967\" class=\"elementor elementor-3967\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ea3dfd elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ea3dfd\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5adfc7f6\" data-id=\"5adfc7f6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-53e8f764 elementor-widget elementor-widget-text-editor\" data-id=\"53e8f764\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><\/p>\n<p>Peptomyc presents results of their Ph1 study of OMO-103 in advanced solid tumours. OMO-103 is an inhibitor for MYC, one of the most wanted, long-considered, undruggable oncogenes. The trial has established the safety, tolerability and pharmacokinetic profile of OMO-103, advising on Ph2 design and identifying soluble factors with the potential as pharmacodynamic and predictive response markers.<\/p>\n<p>\u00a0<\/p>\n<p><\/p>\n<p><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41591-024-02805-1.epdf?sharing_token=Kb6gG5E9yqkeIKGERvlDs9RgN0jAjWel9jnR3ZoTv0PbA8JGCp8lm6FKJ7Jh-32YH7J2xVsk_KGC2EJRU1fEovpCc4NhoH9mLlaGUrqCoPgvJZNKyZVnNLFM1UXLoCexi1Zxi7bZ2rOl-ZxWgZOy8orQl2v1yuum2gO9zR0Zarg%3D\" target=\"_blank\" rel=\"noopener\">Read more<\/a><\/p>\n<p><\/p>\n<p><\/p>\n<div style=\"height: 50px;\" aria-hidden=\"true\">\u00a0<\/div>\n<p><\/p>\n<p><\/p>\n<hr \/>\n<p><\/p>\n<p><\/p>\n<div style=\"height: 100px;\" aria-hidden=\"true\">\u00a0<\/div>\n<p><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Peptomyc presents results of their Ph1 study of OMO-103 in advanced solid tumours. OMO-103 is an inhibitor for MYC, one of the most wanted, long-considered, undruggable oncogenes. The trial has established the safety, tolerability and pharmacokinetic profile of OMO-103, advising on Ph2 design and identifying soluble factors with the potential as pharmacodynamic and predictive response [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":3949,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[24],"tags":[],"class_list":["post-3967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-portfolio"],"acf":[],"_links":{"self":[{"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=\/wp\/v2\/posts\/3967","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3967"}],"version-history":[{"count":0,"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=\/wp\/v2\/posts\/3967\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=\/wp\/v2\/media\/3949"}],"wp:attachment":[{"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/staging.aliathbio.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}